Pr

79-0324. Overstreet, R. M.; Howse, H. D. (Parasitol. Seu,
Gulf Coast Res. Lab., Ocean Springs, MS 29564) Some para-
sites and diseases of estuarine fishes in polluted habitats of
Mississippi. vdan. N.Y. stead. Sci. 298. 427-462: 1977. (98
references)

A review is presented of a series of studies on diseases
of shellfish and finfish in estuaries suspected of or known t0-
be polluced with organophosphorous and chlorinated hydro-
carbon insecticides (chlordane, endrin, and DDT), oil, phe-
nols, heavy metals and/or sewage. Diseases observed were
lymphocystis, neoplasia, hyperplasia, sarous viral and hac-
terial infections, as well as many parasitic infecuons insol ung
helminths and protoczotns. The authors siale that pollutants

—ecan cause disease directly, resulang to acute to chronic dts

ease. Indirect causation can also occur, resulting (rom fish
becoming weakened and having their defenses lowered.
When this occurs, the animals become Cuinerable to parasites
and other disease agents. The paper does not report cause and
eHect relationships, nor does it relate speeic diseases to spe-
ctlig pollutants,

79-0325. Newhouse, Mc McEvoy, D2 Rosenthal D.
(Dep. Med.. St. Joseph Hosp., Hamilton, Ont, Cunaday Per-
cutaneous paritquat absorption, cireA. Dermatol 14010):
IS16-1S19. 1978. (20 references)
A 3% ald woman, who frequently worked with
paraquat i orchards, was admitted ta the hospind after mi-
bor scratches on her arms and less developed raised lesions,
jeauding clear or bloody tuids Other symploms meiuded
headache, breathlessness, chest tightness. anoresia and
Pweight loss. Biopsy from the ulcerated lesions showed necro.
sisotthe epidermis and dermis, Pulmonary function studies
revealed moderate restrictive ventilatory defect. Within 14
days of topical therapy with Burrow's solution conmipeess and
petroleum gauze, marked improvement was evident and she
Was sent home. Seventeen duys later she was readmitted with
symptoms of dyspnea, cough, fever, nausea/somiting, and
new lesions. Progressive deterioration included hepatic and
remil dysfuncuion, emtensive coagulative necrosis of the skin
downto the fat, and respiratory fatlure. She died 12 days
tater. Histropachological findings, together with similarities to
previously described paraquat poisoning in animals pointed
to pesticide poisoning. Studies have shown that paraquat is
normally not inhaled to toxic doses during normal apphea-
tion. Presumably only small quantities at uny one time were
absorbed by the woman's skin, however, the cumulative doses
may have been considerable. The long term interval between
exposure and death may have been due to small doses and
the route of entry of the pesticide.

79-0326. Mendelsohn. Hu: Paz, UL (Den. Zool, Tel-Aviv
Univ, Tel-Aviv, Israel) Mass mortality of birds of prey

“Lub. Med. M.D. Anderson Hosp. & Tumor Inst. Houston

persistent organophosphorus pesticides already pres: rth
environment is reported in the Huleh Valley in IsaBel witk
the affected species having raptors and owls which had fe
on Azodrin (monacrotophos) poisoned voles and birds. Th
pesticide had been used on fields of alfalfa in an effort t
comtrol a massive infestation of voles which were destroyin
the crop completely in some places. While this pesticide is
recommended for use in (seach only tor the control of pests
on cotton and in orchards, the dangers of the cnemical tc
wildlife do not appear in the Hebrew translation on the origi.
nal label. About 400 birds: of prey were destroyed on an &
kimé area within a three mo period. .

79-0327, Youness, Ea; Ahearn, MoJ.; Drewinko, B. (Dep
TX 77030) Simultaneous occurrence of non-Hodgkin’s lym
phoma and spontaneous acute granulocytic leukemia. -{, 4
Clin, Pathol, 7003): 415-420: 1978. (32 references)

A case is presented in which a 67-yr old farmer whel
experienced chronic exposure to some form of insecticide su
fered from weakness, anemia, and fluctuating platelet ined
Following eatensive testing, his condition was diagnosed as
non-Hodgkins lymphoma with superimposed acute granulo
vytc leukemia. A discusston, of the treatmentas given. This
Is the second case af these two diseases occurring simultaned
ously in the absence ofa history of chemothersgs, radiotheral
py, or both. [ets suspected that the chronig caposure tear

unknown insectigide may hase plaved a leulomeucnre cofer

79-0328, Shea. Poo (Pac. Southwest Por & ange Far
Stn, USDA For Serv. Dave, CN 9S6t6) Testing of chemi
cal and microbial insecticides for safety. Some techniques
Bull, Entomol, Sov. Ant ISS): V76-17X 1977 (8 references.

A cooperative three year study was started in 197
to investigate the effects of ‘aree chemical insecticides. dim
hin (difubenzuron), orthene (acephate), and sevin (earbary!
t-oil on nontarget organisms found in a typical eastern Ore
gon Douglas fir’mixed conifer forest. The deposit of sora
was monitored and analyses were curried out on all plots fo
all maternls in the residue study including the Douglas-fir’
alder, grass, soil, stream sediment. and water. Studies wer
made on ants, yellowjackets, domestic bees and wild pollina
tors ulong with selected forest Diptera. The aquatic insec-
populations were studied by several sampling regimes an
techniques Studies were alsa made of mammals and bird
in the arca sprayed. The results of this study are expected t
be exceedingly complete due to the comprehensiveness of th
investigation. One major strength of the studies is the coopet
itive and coordinated manner under which the whole projec
has been conducted.

79-0329, Hayes, W.J. Jr, Vaughn, W. K. (Sch. Med. Var
derbiit Univ.. Nashville, TN 37232) Mortality from pest
. LT