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Malathion Intoxication in Military Seout Dogs” °%

mn AM, MeCurnin, DVM. 4 WLUTE O MALATI
FARALYS s TIS —
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2 AEMSRRNAGIO T) is me OP

a>) MRRY CONGEST
BINS OL, caus
AHYPERTRO PAY 7 Le hte
SAT TR 1S = CARLIA oF S74 ee ‘Egeuacoe SUMMARY
Twenty-four military seout dogs were inadvertently &xposed to 1 or
more inadequately diluted matlathion-dip Solutions. Of the 24 dogs, 14 died, qj
‘8 recovered, and 2 were euthanatized, The therapeutic approach was to -
remove the unabsorbed toxicant (vig soap bath), reactivate the inactivated
cholinesterase (via pyridine-2-aldoxime*), block the excessive cholinergic
response (via atropine sulfate), and give symptomatic treatment to con-
; . ; _
trol the secondary complications that developed, 40 DAVS oF TREATMEN Zp
) LAYS 3)

OF £4 Dg6S5 IMYILVEDO Dy R plu ‘erie MEE: 2

FS RECOVERED /ye DiEO & SX WERE DESTROYED, CE Sr ORGE

TWENTY-ProuR SCOUT DOGS of the 34th In- excessive salivation. The remaining 23
fantry Platoon (Scout Dog), An Khe, dogs appeared clinically normal. Sympto-
Republic of South Vietnam, were ex- matic treatment was’ given to the jl
posed to inadequately diluted malathion- patient in the form of 5% dextrose in

dip solutions administered on one or more’ saline solution and penicillin-dihydro-

of the following dates: Noy, 3, 4, and 1 1, streptomycin. The patient's condition re-

1967. The solution was inadvertently - mained unchanged during the day, and

made up by adding an unmeasured he was found dead the following morn-
amount of malathion (57% concentrate) ing, Necropsy findings included gastritis,

to a previously Prepared solution of enteritis, colitis, anc une con.
malathion and water. The previously gestion.

Prepared solution had been left in an During the night, 5 additional dogs i
Open vat and diluted by rain a few days hecame i, Clinical signs for these dozs :
before it was Strengthened. The final included salivation, anorexia,” muscle NORE -.
Concentration was unknown, but could tremors, convulsions, malaise, arched
have been as much as 15% malathion. jacK, elevated body temperature, and
A 0.25 to 0.5% malathion solution has some vomition. Symptomatic treatnient
. Commonly been used in the treatment was given. TRe 3 most critical patients
and control of ticks in military scout and were moved into the barracks toe get them
sentry dogs. . off the damp cement. Immediately prior
to the onset of illness, there had been 5
Case Reports trointestinad ee aet cold ain wae Aas

‘ . tointestinal syndrome was thought to
, The first dog affected was found re- have been initinted hy stress from ihe in-
ent en NON sre clement weather, At the time, the dipping
clinical signs were extheme weakness and that Ped aed pctltYs, before was not as-
: oes sociated with the problem.

Clinical data were collected by Dr. MeCurnin while serv. On day 4, the condition of the 3 most
Sram Bee Meco ai he Meat yg agents had not improved, hut
at Veterinary CRnient Sviences, Colove of Vetorinary Merl the other 2 dogs were responding Satis
fee, Towa State University, Ames, lowa Su, factorily, Supportive therapy Was con-

* Protapaimn chloride injectable, Ayorst Taboraterfos, New .
York, NVY, tinued.

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at
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October 15, 1949 1359